Component of RQC, which mediates nascent chain degradation; RQC (ribosome quality control complex) is a ribosome-bound complex required for degradation of polypeptides arising from stalled translation; recruits alanine- and threonine-charged tRNA to the A site and directs the elongation of nascent chains independently of mRNA or 40S subunits; monitors translation stress and signals this to Hsf1p [Source:SGD;Acc:S000005930]

Chromosome XVI: 535,820-538,936 reverse strand.

R64-1-1:BK006949.2

This gene has 1 transcript (splice variant), 380 orthologues and is a member of 2 Ensembl protein families.

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