Multistep regulator of cAMP-PKA signaling; inhibits PKA downstream of Gpa2p and Cyr1p, thereby increasing cAMP dependency; promotes ubiquitin-dependent proteolysis of Ira2p; regulated by G-alpha protein Gpa2p; GPB1 has a paralog, GPB2, that arose from the whole genome duplication [Source:SGD;Acc:S000005898]

KRH2

Chromosome XV: 1,031,489-1,034,182 reverse strand.

R64-1-1:BK006948.2

This gene has 1 transcript (splice variant), 10 orthologues and 1 paralogue.

Show transcript tableHide transcript table