Cytoplasmic and mitochondrial alanyl-tRNA synthetase; required for protein synthesis; point mutation (cdc64-1 allele) causes cell cycle arrest at G1; lethality of null mutation is functionally complemented by human homolog AARS; mutations in human homolog AARS are associated with autoimmune disease polymyositis/dermatomyositis [Source:SGD;Acc:S000005862]
CDC64
Chromosome XV: 946,233-949,109 reverse strand.
R64-1-1:BK006948.2
This gene has 1 transcript (splice variant), 399 orthologues and 1 paralogue.