Saccharomyces cerevisiae (R64-1-1)

Mitochondrial DNA polymerase gamma; single subunit of mitochondrial DNA polymerase in yeast, in contrast to metazoan complex of catalytic and accessory subunits; polymorphic in yeast, petites occur more frequently in some lab strains; human ortholog POLG complements yeast mip1 mutant; mutations in human POLG associated with Alpers-Huttenlocher syndrome (AHS), progressive external ophthalmoplegia (PEO), parkinsonism, other mitochondrial diseases [Source:SGD;Acc:S000005857]

Gene Synonyms

mitochondrial DNA polymerase catalytic subunit


Chromosome XV: 939,621-943,385 reverse strand.


About this gene

This gene has 1 transcript (splice variant) and 354 orthologues.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
Protein coding
P15801 -Ensembl Canonical