ATP-dependent DNA translocase involved in chromatin remodeling; ATPase component that, with Itc1p, forms a complex required for repression of a-specific genes, INO1, and early meiotic genes during mitotic growth; the Isw2 complex exhibits basal levels of chromatin binding throughout the genome as well as target-specific chromatin interactions; targeted by Ume6p- and Sua7p-dependent DNA looping to many loci genome-wide [Source:SGD;Acc:S000005831]
Chromosome XV: 884,514-887,876 forward strand.
R64-1-1:BK006948.2
This gene has 1 transcript (splice variant), 374 orthologues, 16 paralogues and is a member of 1 Ensembl protein family.