Saccharomyces cerevisiae (R64-1-1)
Description

Involved in nuclear migration, part of the dynein/dynactin pathway; targets dynein to microtubule tips, which is necessary for sliding of microtubules along bud cortex; serves at interface between dynein's ATPase site and its microtubule binding stalk, causing individual dynein motors to remain attached to microtubules for long periods; synthetic lethal with bni1; homolog of human LIS1, mutations in which cause the severe brain disorder lissencephaly [Source:SGD;Acc:S000005795]

Location

Chromosome XV: 826,385-827,869 forward strand.

R64-1-1:BK006948.2

About this gene

This gene has 1 transcript (splice variant), 244 orthologues, 1 paralogue and is a member of 3 Ensembl protein families.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
PAC1YOR269W_mRNA1485494aaYOR269W
 
Protein coding
P39946 NM_001183688.1
NP_014912.1

Gene-based displays