Saccharomyces cerevisiae (R64-1-1)
Description

Mitochondrial matrix cochaperone; nucleotide release factor for Ssc1p in protein translocation and folding; also acts as cochaperone for Ssq1p in folding of Fe-S cluster proteins; acts as oxidative sensor to regulate mitochondrial Ssc1p; in presence of oxidative stress, dimeric Mge1p becomes a monomer and unable to regulate Ssc1p function; homolog of E. coli GrpE and human Mge1 (GRPEL1), which also responds to oxidative stress [Source:SGD;Acc:S000005758]

Synonyms

GRPE, YGE1

Location

Chromosome XV: 774,573-775,259 forward strand.

R64-1-1:BK006948.2

About this gene

This gene has 1 transcript (splice variant), 227 orthologues and is a member of 3 Ensembl protein families.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
MGE1YOR232W_mRNA687228aaYOR232W
 
Protein coding
P38523 NM_001183651.3
NP_014875.3

Gene-based displays