Mitochondrial matrix cochaperone; nucleotide release factor for Ssc1p in protein translocation and folding; also acts as cochaperone for Ssq1p in folding of Fe-S cluster proteins; acts as oxidative sensor to regulate mitochondrial Ssc1p; in presence of oxidative stress, dimeric Mge1p becomes a monomer and unable to regulate Ssc1p function; homolog of E. coli GrpE and human Mge1 (GRPEL1), which also responds to oxidative stress [Source:SGD;Acc:S000005758]

GRPE, YGE1

Chromosome XV: 774,573-775,259 forward strand.

R64-1-1:BK006948.2

This gene has 1 transcript (splice variant), 227 orthologues and is a member of 3 Ensembl protein families.

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