Saccharomyces cerevisiae (R64-1-1)
Description

Mitochondrial protein required for iron-sulfur protein synthesis; performs scaffolding function during Fe/S cluster assembly; involved in Fe-S cluster assembly for both mitochondrial and cytosolic proteins; protein abundance increases under DNA replication stress; ISU2 has a paralog, ISU1, that arose from the whole genome duplication; isu1 isu2 double mutant is inviable; human homolog ISCU implicated in mitochondrial myopathy, can complement isu1 isu2 double mutant [Source:SGD;Acc:S000005752]

Synonyms

NUA2

Location

Chromosome XV: 761,614-762,084 reverse strand.

R64-1-1:BK006948.2

About this gene

This gene has 1 transcript (splice variant), 269 orthologues, 1 paralogue and is a member of 1 Ensembl protein family.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
ISU2YOR226C_mRNA471156aaYOR226C
 
Protein coding
Q12056 NM_001183645.3
NP_014869.3

Gene-based displays