Mitochondrial protein required for iron-sulfur protein synthesis; performs scaffolding function during Fe/S cluster assembly; involved in Fe-S cluster assembly for both mitochondrial and cytosolic proteins; protein abundance increases under DNA replication stress; ISU2 has a paralog, ISU1, that arose from the whole genome duplication; isu1 isu2 double mutant is inviable; human homolog ISCU implicated in mitochondrial myopathy, can complement isu1 isu2 double mutant [Source:SGD;Acc:S000005752]
NUA2
Chromosome XV: 761,614-762,084 reverse strand.
R64-1-1:BK006948.2
This gene has 1 transcript (splice variant), 362 orthologues and 1 paralogue.
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
ISU2 | YOR226C_mRNA | 471 | 156aa | YOR226C | Protein coding | Q12056 | - | Ensembl Canonical, |