Imidazoleglycerol-phosphate dehydratase; catalyzes the sixth step in histidine biosynthesis; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts; transcription is regulated by general amino acid control via Gcn4p [Source:SGD;Acc:S000005728]
HIS10, HIS8
Chromosome XV: 721,946-722,608 forward strand.
R64-1-1:BK006948.2
This gene has 1 transcript (splice variant), 332 orthologues and is a member of 2 Ensembl protein families.