Saccharomyces cerevisiae (R64-1-1)
Description

SUMO E3 ligase; catalyzes sumoylation of Yku70p/80p and Sir4p promoting telomere anchoring to the nuclear envelope and regulating telomerase activity; DNA-bound form catalyzes a DNA-damaged triggered sumoylation wave resulting in multisite modification of several DNA repair proteins, enhancing interactions between these proteins and accelerating repair; sumoylates Cse4p, a prerequisite for STUbL-mediated Ub-dependent degradation; role in telomere length maintenance [Source:SGD;Acc:S000005682]

Synonyms

SIZ2

Location

Chromosome XV: 628,360-630,540 reverse strand.

R64-1-1:BK006948.2

About this gene

This gene has 1 transcript (splice variant), 236 orthologues, 1 paralogue and is a member of 2 Ensembl protein families.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
NFI1YOR156C_mRNA2181726aaYOR156C
 
Protein coding
Q12216 NM_001183575.1
NP_014799.1

Gene-based displays