Saccharomyces cerevisiae (R64-1-1)
Description

Profilin; binds actin, phosphatidylinositol 4,5-bisphosphate, and polyproline regions; involved in cytoskeleton organization; required for normal timing of actin polymerization in response to thermal stress; protein abundance increases in response to DNA replication stress; highly conserved protein; human PFN1 (profilin 1) complements temperature sensitive pfy1 mutants, PFN1 mutations are a rare cause of ALS [Source:SGD;Acc:S000005648]

Synonyms

PRF1

Location

Chromosome XV: 552,298-552,887 reverse strand.

R64-1-1:BK006948.2

About this gene

This gene has 1 transcript (splice variant), 224 orthologues and is a member of 2 Ensembl protein families.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
PFY1YOR122C_mRNA381126aaYOR122C
 
Protein coding
P07274 NM_001183541.3
NP_014765.3

Gene-based displays