Saccharomyces cerevisiae (R64-1-1)

Serine kinase involved in cell cycle regulation and rDNA integrity; associated with late pre-40S particles via its conserved C-terminal domain and participates in late 40S biogenesis; association with pre-40S particles regulated by its catalytic ATPase site and likely occurs after the release of Rio2p from these particles; involved in cell cycle progression and processing of the 20S pre-rRNA into mature 18S rRNA; phosphorylates Rpa43p in anaphase to remove Pol I from rDNA [Source:SGD;Acc:S000005645]

Gene Synonyms



Chromosome XV: 548,792-550,246 reverse strand.


About this gene

This gene has 1 transcript (splice variant), 362 orthologues and 1 paralogue.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
Protein coding
Q12196 -Ensembl Canonical