Saccharomyces cerevisiae (R64-1-1)
Description

Endosomal Rab family GTPase; required for endocytic transport and sorting of vacuolar hydrolases; required for endosomal localization of the CORVET complex; required with YPT52 for MVB biogenesis and sorting; involved in autophagy and ionic stress tolerance; geranylgeranylation required for membrane association; protein abundance increases in response to DNA replication stress; mammalian Rab5 homolog; VPS21 has a paralog, YPT53, that arose from the whole genome duplication [Source:SGD;Acc:S000005615]

Synonyms

VPS12, VPT12, YPT21, YPT51

Location

Chromosome XV: 490,196-490,828 reverse strand.

R64-1-1:BK006948.2

About this gene

This gene has 1 transcript (splice variant), 260 orthologues, 1 paralogue and is a member of 2 Ensembl protein families.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
VPS21YOR089C_mRNA633210aaYOR089C
 
Protein coding
P36017 NM_001183508.1
NP_014732.1

Gene-based displays