Nuclear 5' to 3' single-stranded RNA exonuclease; involved in RNA metabolism, including rRNA and snoRNA processing, as well as poly (A+) dependent and independent mRNA transcription termination; required for cotranscriptional pre-rRNA cleavage; displaces Cdk1p from elongating transcripts, especially as RNAPII reaches the poly(A) site, negatively regulates phosphorylation of the CTD of RNAPII, and inhibits RNAPII transcriptional elongation [Source:SGD;Acc:S000005574]

HKE1, TAP1, XRN2

Chromosome XV: 418,630-421,650 reverse strand.

R64-1-1:BK006948.2

This gene has 1 transcript (splice variant), 254 orthologues, 1 paralogue and is a member of 2 Ensembl protein families.

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