5'-3' exonuclease and flap-endonuclease; involved in recombination, double-strand break repair, MMS2 error-free branch of the post replication (PRR) pathway and DNA mismatch repair; role in telomere maintenance; member of the Rad2p nuclease family, with conserved N and I nuclease domains; relative distribution to the nucleus increases upon DNA replication stress; EXO1 has a paralog, DIN7, that arose from the whole genome duplication [Source:SGD;Acc:S000005559]
DHS1
Chromosome XV: 392,416-394,524 reverse strand.
R64-1-1:BK006948.2
This gene has 1 transcript (splice variant), 369 orthologues, 4 paralogues and is a member of 1 Ensembl protein family.
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
EXO1 | YOR033C_mRNA | 2109 | 702aa | YOR033C | Protein coding | P39875 | - | Ensembl Canonical, |