Saccharomyces cerevisiae (R64-1-1)
Description

DDHD domain-containing phospholipase A1; mitochondrial matrix enzyme with sn-1-specific activity, hydrolyzing cardiolipin, PE, PC, PG and PA; implicated in remodeling of mitochondrial phospholipids; antagonistically regulated by Aft1p and Aft2p; in humans, mutations in DDHD1 and DDHD2 genes cause specific types of hereditary spastic paraplegia, while DDL1-defective yeast share similar phenotypes such as mitochondrial dysfunction and defects in lipid metabolism [Source:SGD;Acc:S000005548]

Location

Chromosome XV: 373,710-375,857 reverse strand.

R64-1-1:BK006948.2

About this gene

This gene has 1 transcript (splice variant), 347 orthologues and is a member of 2 Ensembl protein families.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
DDL1YOR022C_mRNA2148715aaYOR022C
 
Protein coding
Q12204 NM_001183441.1
NP_014665.1

Gene-based displays