Plasma membrane sterol transporter of the ATP-binding cassette family; required, along with Pdr11p, for uptake of exogenous sterols and their incorporation into the plasma membrane; activity is stimulated by phosphatidylserine; sterol uptake is required for anaerobic growth because sterol biosynthesis requires oxygen; AUS1 has a paralog, PDR11, that arose from the whole genome duplication [Source:SGD;Acc:S000005537]
Chromosome XV: 349,679-353,863 forward strand.
R64-1-1:BK006948.2
This gene has 1 transcript (splice variant), 528 orthologues and 9 paralogues.
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
AUS1 | YOR011W_mRNA | 4185 | 1394aa | YOR011W | Protein coding | Q08409 | - | Ensembl Canonical, |