mRNA cap binding protein and translation initiation factor eIF4E; the eIF4E-cap complex is responsible for mediating cap-dependent mRNA translation via interactions with translation initiation factor eIF4G (Tif4631p or Tif4632p); protein abundance increases in response to DNA replication stress; mutants are defective for adhesion and pseudohyphal growth; human homolog EIF4E can complement yeast cdc33 null mutant [Source:SGD;Acc:S000005499]
eIF4E, TIF45
Chromosome XV: 60,383-61,024 reverse strand.
R64-1-1:BK006948.2
This gene has 1 transcript (splice variant) and 271 orthologues.
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
CDC33 | YOL139C_mRNA | 642 | 213aa | YOL139C | Protein coding | P07260 | - | Ensembl Canonical, |