Saccharomyces cerevisiae (R64-1-1)

Subunit of SEACAT, a subcomplex of the SEA complex; Rtc1p, along with Mtc5p and Sea4p, redundantly inhibit the TORC1 inhibitory role of the Iml1p/SEACIT (Iml1p-Npr2p-Npr3p) subcomplex, a GAP for GTPase Gtr1p (EGOC subunit) in response to amino acid limitation, thereby resulting in activation of TORC1 signaling; SEA is a coatomer-related complex that associates dynamically with the vacuole; has N-terminal WD-40 repeats and a C-terminal RING motif; null suppresses cdc13-1 [Source:SGD;Acc:S000005498]

Gene Synonyms



Chromosome XV: 61,325-65,350 reverse strand.


About this gene

This gene has 1 transcript (splice variant), 257 orthologues and 6 paralogues.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
Protein coding
Q08281 -Ensembl Canonical