GTPase-activating protein; negatively regulates RAS by converting it from the GTP- to the GDP-bound inactive form, required for reducing cAMP levels under nutrient limiting conditions; IRA2 has a paralog, IRA1, that arose from the whole genome duplication; defects in human homolog NF1 are associated with neurofibromatosis [Source:SGD;Acc:S000005441]
CCS1, GLC4
Chromosome XV: 171,070-180,309 forward strand.
R64-1-1:BK006948.2
This gene has 1 transcript (splice variant), 117 orthologues and 2 paralogues.