GTPase-activating protein; negatively regulates RAS by converting it from the GTP- to the GDP-bound inactive form, required for reducing cAMP levels under nutrient limiting conditions; IRA2 has a paralog, IRA1, that arose from the whole genome duplication; defects in human homolog NF1 are associated with neurofibromatosis [Source:SGD;Acc:S000005441]

CCS1, GLC4

Chromosome XV: 171,070-180,309 forward strand.

R64-1-1:BK006948.2

This gene has 1 transcript (splice variant), 219 orthologues, 2 paralogues and is a member of 2 Ensembl protein families.

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