Guanine nucleotide exchange factor (GEF); activates Sar1p by catalyzing the exchange of GDP for GTP; required for the initiation of COPII vesicle formation in ER to Golgi transport; glycosylated integral membrane protein of the ER; SEC12 has a paralog, SED4, that arose from the whole genome duplication [Source:SGD;Acc:S000005309]

SED2

Chromosome XIV: 673,274-674,689 reverse strand.

R64-1-1:BK006947.3

This gene has 1 transcript (splice variant), 137 orthologues and 2 paralogues.

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