Subunit of heterotrimeric Replication Protein A (RPA); RPA is a highly conserved single-stranded DNA binding protein involved in DNA replication, repair, and recombination; RPA protects against inappropriate telomere recombination, and upon telomere uncapping, prevents cell proliferation by a checkpoint-independent pathway; in concert with Sgs1p-Top2p-Rmi1p, stimulates DNA catenation/decatenation activity of Top3p; protein abundance increases in response to DNA replication s [Source:SGD;Acc:S000005256]

BUF1, RPA2

Chromosome XIV: 48,287-49,216 forward strand.

R64-1-1:BK006947.3

This gene has 1 transcript (splice variant), 228 orthologues and is a member of 2 Ensembl protein families.

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