Subunit of a replication-pausing checkpoint complex; Tof1p-Mrc1p-Csm3p acts at the stalled replication fork to promote sister chromatid cohesion after DNA damage, facilitating gap repair of damaged DNA; interacts with the MCM helicase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000005217]
Chromosome XIV: 122,883-126,599 forward strand.
R64-1-1:BK006947.3
This gene has 1 transcript (splice variant) and 340 orthologues.
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
TOF1 | YNL273W_mRNA | 3717 | 1238aa | YNL273W | Protein coding | P53840 | - | Ensembl Canonical, |