Essential protein that forms a complex with Rli1p and Yae1p; ortholog of human ORAOV1, which is overexpressed in solid tumors; inviability of null mutant under standard conditions is complemented by overexpression of ORAOV1; essential for growth under standard (aerobic) conditions but not under anaerobic conditions; may have a role in protection of ribosomal assembly and function from damage due to reactive oxygen species [Source:SGD;Acc:S000005204]

Chromosome XIV: 156,859-157,455 reverse strand.

R64-1-1:BK006947.3

This gene has 1 transcript (splice variant), 53 orthologues and is a member of 2 Ensembl protein families.

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