Saccharomyces cerevisiae (R64-1-1)

Peripheral membrane protein needed for Golgi-to-ER retrograde traffic; mediates Sey1p-independent homotypic ER fusion; forms Dsl1 tethering complex with Sec39p and Tip20p that forms a stable complex with ER SNAREs Sec20p, Ufe1p and Use1p and is functionally conserved from yeast to mammalian cells; component of the ER target site that interacts with coatomer; interacts with different subunits of COPI vesicle coat; interacts with Cin5p; homolog of fly and human ZW10 gene [Source:SGD;Acc:S000005202]

Gene Synonyms



Chromosome XIV: 158,109-160,373 reverse strand.


About this gene

This gene has 1 transcript (splice variant) and 18 orthologues.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
Protein coding
P53847 -Ensembl Canonical