Essential DNA-binding transcription regulator that binds many loci; involved in transcription activation, repression, chromatin silencing, telomere length maintenance; relocalizes to cytosol under hypoxia; conserved protein with N-terminal BRCT domain, central region with homology to Myb DNA binding domain, and C-terminal Rap1-specific protein-interaction domain (RCT domain); recruits Sir complex to telomeric DNA; present in quiescent cell telomere hyperclusters [Source:SGD;Acc:S000005160]

GRF1, TBA1, TUF1

Chromosome XIV: 241,689-244,172 forward strand.

R64-1-1:BK006947.3

This gene has 1 transcript (splice variant) and 43 orthologues.

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