RNA binding protein that sequesters CLN3 mRNA in cytoplasmic foci; regulates genes involved in the cell cycle, sister chromatid cohesion, and stress response; acts as a cytoplasmic retention factor for Cdc28p and associated cyclins; regulates cell fate and dose-dependently regulates the critical cell size required for passage through Start; Tpk1p (PKA) mediated phosphorylation (S568) inhibits Whi3p function, decreasing its interaction with CLN3 mRNA; regulates ploidy [Source:SGD;Acc:S000005141]
Chromosome XIV: 267,608-269,593 reverse strand.
R64-1-1:BK006947.3
This gene has 1 transcript (splice variant), 59 orthologues, 2 paralogues and is a member of 1 Ensembl protein family.
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
WHI3 | YNL197C_mRNA | 1986 | 661aa | YNL197C | Protein coding | P34761 | - | Ensembl Canonical, |