CAP (cyclase-associated protein); N-terminus binds adenylate cyclase and facilitates activation by RAS; N-terminus forms novel hexameric star-shaped shuriken structures that directly catalyze cofilin-mediated severing of actin filaments; C-terminus binds and recycles cofilin bound, ADP-actin monomers, facilitating regulation of actin dynamics and cell morphogenesis; N- and C-termini can function as physically separate proteins; mCAP1 is the mouse homolog [Source:SGD;Acc:S000005082]
CAP
Chromosome XIV: 366,741-368,321 forward strand.
R64-1-1:BK006947.3
This gene has 1 transcript (splice variant), 353 orthologues and is a member of 1 Ensembl protein family.
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
SRV2 | YNL138W_mRNA | 1581 | 526aa | YNL138W | Protein coding | P17555 | - | Ensembl Canonical, |