Saccharomyces cerevisiae (R64-1-1)
Description

Ubiquitin-protein ligase (E3); controls septin dynamics and spindle position checkpoint (SPOC) with ligase Dma1p by regulating recruitment of Elm1p to bud neck; regulates levels of eIF2 subunit Gcd11p, as well as abundance, localization, and ubiquitination of Cdk inhibitory kinase Swe1p; ortholog of human RNF8, similar to human Chfr; contains FHA and RING finger domains; DMA2 has a paralog, DMA1, that arose from the whole genome duplication [Source:SGD;Acc:S000005060]

Synonyms

CHF2

Location

Chromosome XIV: 408,341-409,909 forward strand.

R64-1-1:BK006947.3

About this gene

This gene has 1 transcript (splice variant), 296 orthologues, 3 paralogues and is a member of 2 Ensembl protein families.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
DMA2YNL116W_mRNA1569522aaYNL116W
 
Protein coding
P53924 NM_001182954.3
NP_014283.3

Gene-based displays