Ubiquitin-protein ligase (E3); controls septin dynamics and spindle position checkpoint (SPOC) with ligase Dma1p by regulating recruitment of Elm1p to bud neck; regulates levels of eIF2 subunit Gcd11p, as well as abundance, localization, and ubiquitination of Cdk inhibitory kinase Swe1p; ortholog of human RNF8, similar to human Chfr; contains FHA and RING finger domains; DMA2 has a paralog, DMA1, that arose from the whole genome duplication [Source:SGD;Acc:S000005060]

CHF2

Chromosome XIV: 408,341-409,909 forward strand.

R64-1-1:BK006947.3

This gene has 1 transcript (splice variant), 165 orthologues, 1 paralogue and is a member of 1 Ensembl protein family.

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