Alpha-isopropylmalate synthase (2-isopropylmalate synthase); the main isozyme responsible for the first step in the leucine biosynthesis pathway; LEU4 has a paralog, LEU9, that arose from the whole genome duplication [Source:SGD;Acc:S000005048]

Chromosome XIV: 424,895-426,754 reverse strand.

R64-1-1:BK006947.3

This gene has 1 transcript (splice variant), 411 orthologues and 3 paralogues.

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