Leucine-zipper transcriptional activator; responsible for regulation of sulfur amino acid pathway; requires different combinations of auxiliary factors Cbf1p, Met28p, Met31p and Met32p; feedforward loop exists in the regulation of genes controlled by Met4p and Met32p; can be ubiquitinated by ubiquitin ligase SCF-Met30p, is either degraded or maintained in an inactive state; regulates degradation of its own DNA-binding cofactors by targeting them to SCF-Met30p [Source:SGD;Acc:S000005047]
Chromosome XIV: 427,735-429,753 forward strand.
R64-1-1:BK006947.3
This gene has 1 transcript (splice variant), 16 orthologues and is a member of 1 Ensembl protein family.