Protein involved in 2'-O-methylation of C32 of substrate tRNAs; interacts with 2'-O-ribose methyltransferase Trm7p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; non-essential gene; yeast null mutant can be functionally complemented by human THADA, mutations in which have been implicated in epithelial thyroid adenomas, type 2 diabetes, and polycystic ovary syndrome (PCOS) [Source:SGD;Acc:S000004872]

Chromosome XIII: 784,621-788,883 reverse strand.

R64-1-1:BK006946.2

This gene has 1 transcript (splice variant), 397 orthologues and is a member of 2 Ensembl protein families.

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