Saccharomyces cerevisiae (R64-1-1)
Description

RING domain E3 ubiquitin ligase; involved in ubiquitin-mediated degradation of non-stop proteins and translationally stalled ER membrane proteins; component of ribosome-bound RQC (ribosome quality control) complex; degrades products of mRNAs lacking a termination codon regardless of a poly(A) tail; functional connections to chromatin modification; homolog of mouse Listerin, mutations in which reported to cause neurodegeneration [Source:SGD;Acc:S000004861]

Synonyms

LTN1

Location

Chromosome XIII: 763,351-768,039 reverse strand.

R64-1-1:BK006946.2

About this gene

This gene has 1 transcript (splice variant), 243 orthologues and is a member of 1 Ensembl protein family.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
RKR1YMR247C_mRNA46891562aaYMR247C
 
Protein coding
Q04781 NM_001182755.1
NP_013975.1

Gene-based displays