Nuclease subunit of the MRX complex with Rad50p and Xrs2p; complex functions in repair of DNA double-strand breaks and in telomere stability; Mre11p associates with Ser/Thr-rich ORFs in premeiotic phase; nuclease activity required for MRX function; widely conserved; forms nuclear foci upon DNA replication stress [Source:SGD;Acc:S000004837]

NGS1, RAD58, XRS4

Chromosome XIII: 718,575-720,653 reverse strand.

R64-1-1:BK006946.2

This gene has 1 transcript (splice variant), 367 orthologues and is a member of 1 Ensembl protein family.

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