GMP synthase; highly conserved enzyme that catalyzes the second step in the biosynthesis of GMP from inosine 5'-phosphate (IMP); transcription is not subject to regulation by guanine but is negatively regulated by nutrient starvation; reduction-of-function mutation gua1-G388D causes changes in cellular guanine nucleotide pools, defects in general protein synthesis, and impaired translation of GCN4 mRNA [Source:SGD;Acc:S000004830]

Chromosome XIII: 701,790-703,367 forward strand.

R64-1-1:BK006946.2

This gene has 1 transcript (splice variant), 368 orthologues and 3 paralogues.

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