Conserved protein involved in autophagy; interacts with Atg12p-Atg5p conjugates to form Atg12p-Atg5p-Atg16p multimers, which binds to membranes and localizes to the pre-autophagosomal structure and are required for autophagy; relocalizes from nucleus to cytoplasmic foci upon DNA replication stress [Source:SGD;Acc:S000004769]

APG15, APG16, CVT11, SAP18

Chromosome XIII: 574,476-574,928 reverse strand.

R64-1-1:BK006946.2

This gene has 1 transcript (splice variant) and 16 orthologues.

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