Saccharomyces cerevisiae (R64-1-1)
Description

Mitochondrial inner membrane m-AAA protease component; mediates degradation of misfolded or unassembled proteins; also required for correct assembly of mitochondrial enzyme complexes; overexpression of human AFG3L2 complements respiratory defect of yeast afg3 yta12 double null mutation, but overexpression of disease-associated AFG3L2 variants does not; expression of both human SPG7 (paraplegin) and AFG3L2 complements yeast yta12 afg3 double mutation [Source:SGD;Acc:S000004695]

Synonyms

RCA1

Location

Chromosome XIII: 445,609-448,086 reverse strand.

R64-1-1:BK006946.2

About this gene

This gene has 1 transcript (splice variant), 238 orthologues, 2 paralogues and is a member of 3 Ensembl protein families.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
YTA12YMR089C_mRNA2478825aaYMR089C
 
Protein coding
P40341 NM_001182589.1
NP_013807.1

Gene-based displays