Saccharomyces cerevisiae (R64-1-1)

ATP-dependent RNA helicase of the SFI superfamily; involved in nonsense mediated mRNA decay; required for efficient translation termination at nonsense codons and targeting of NMD substrates to P-bodies; binds to the small ribosomal subunit via an interaction with Rps26; forms cytoplasmic foci upon DNA replication stress [Source:SGD;Acc:S000004685]

Gene Synonyms

IFS2, MOF4, SUP113, UPF1


Chromosome XIII: 426,712-429,627 reverse strand.


About this gene

This gene has 1 transcript (splice variant), 292 orthologues and 4 paralogues.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
Protein coding
P30771 -Ensembl Canonical