Transcriptional regulator; facilitates elongation through factors that modify RNAP II; role in peroxide resistance involving Rad2p; role in nonhomologous end-joining (NHEJ) of ds breaks in plasmid DNA, but not chromosomal DNA; role in the hyperosmotic stress response through polymerase recruitment at RNAP II and RNAP III genes; negatively regulates sporulation; protein abundance increases in response to DNA replication stress; functionally complemented by human SUB1 (PC4) [Source:SGD;Acc:S000004642]
TSP1
Chromosome XIII: 348,644-349,522 reverse strand.
R64-1-1:BK006946.2
This gene has 1 transcript (splice variant), 150 orthologues and is a member of 2 Ensembl protein families.
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
SUB1 | YMR039C_mRNA | 879 | 292aa | YMR039C | Protein coding | P54000 | NM_001182536.1 NP_013753.1 |