Saccharomyces cerevisiae (R64-1-1)

PtdIns-3-P binding protein that tethers the ER to vacuoles at NVJs; anchored in the ER membrane at nucleus-vacuole junctions and binds phosphatidylinositol 3-phosphate (PtdIns-3-P) in the vacuolar membrane via its Phox homology (PX) domain; expressed predominantly in late G1 to early S phase of the cell cycle; mutation affects nuclear and mitochondrial transmission to daughter buds; similar to 4 human genes, one of which (SNX14) is associated with neurological disease [Source:SGD;Acc:S000004572]


Chromosome XIII: 58,939-62,322 reverse strand.


About this gene

This gene has 1 transcript (splice variant) and 347 orthologues.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
Protein coding
Q01846 -Ensembl Canonical