PtdIns-3-P binding protein that tethers the ER to vacuoles at NVJs; anchored in the ER membrane at nucleus-vacuole junctions and binds phosphatidylinositol 3-phosphate (PtdIns-3-P) in the vacuolar membrane via its Phox homology (PX) domain; expressed predominantly in late G1 to early S phase of the cell cycle; mutation affects nuclear and mitochondrial transmission to daughter buds; similar to 4 human genes, one of which (SNX14) is associated with neurological disease [Source:SGD;Acc:S000004572]

Chromosome XIII: 58,939-62,322 reverse strand.

R64-1-1:BK006946.2

This gene has 1 transcript (splice variant), 218 orthologues and is a member of 2 Ensembl protein families.

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