Large subunit of trehalose 6-phosphate synthase/phosphatase complex; Tps1p-Tps2p complex converts uridine-5'-diphosphoglucose and glucose 6-phosphate to trehalose; contributes to survival to acute lethal heat stress; mutant has aneuploidy tolerance; protein abundance increases in response to DNA replication stress; TSL1 has a paralog, TPS3, that arose from the whole genome duplication [Source:SGD;Acc:S000004566]
Chromosome XIII: 70,624-73,920 forward strand.
R64-1-1:BK006946.2
This gene has 1 transcript (splice variant), 352 orthologues, 3 paralogues and is a member of 1 Ensembl protein family.