Guanine nucleotide exchange factor (GEF) and ubiquitin receptor; involved in vesicle-mediated vacuolar transport, including Golgi-endosome trafficking and sorting through the multivesicular body (MVB); stimulates the intrinsic guanine nucleotide exchange activity of Rab family members (Vps21p/Ypt52p/Ypt53p); partially redundant with GEF MUK1; required for localization of the CORVET complex to endosomes; similar to mammalian ras inhibitors; contains a Ub-interacting CUE domain [Source:SGD;Acc:S000004563]

VPL31, VPT9

Chromosome XIII: 78,335-79,690 reverse strand.

R64-1-1:BK006946.2

This gene has 1 transcript (splice variant), 348 orthologues, 1 paralogue and is a member of 1 Ensembl protein family.

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