Basic leucine zipper (bZIP) transcription factor; required for oxidative stress tolerance; activated by H2O2 through the multistep formation of disulfide bonds and transit from the cytoplasm to the nucleus; Yap1p is degraded in the nucleus after the oxidative stress has passed; mediates resistance to cadmium; relative distribution to the nucleus increases upon DNA replication stress; YAP1 has a paralog, CAD1, that arose from the whole genome duplication [Source:SGD;Acc:S000004466]

PAR1, SNQ3

Chromosome XIII: 253,848-255,800 forward strand.

R64-1-1:BK006946.2

This gene has 1 transcript (splice variant), 366 orthologues and is a member of 2 Ensembl protein families.

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