Zinc-knuckle transcription factor, repressor and activator; regulates genes involved in branched chain amino acid biosynthesis and ammonia assimilation; acts as a repressor in leucine-replete conditions and as an activator in the presence of alpha-isopropylmalate, an intermediate in leucine biosynthesis that accumulates during leucine starvation [Source:SGD;Acc:S000004443]
Chromosome XII: 1,036,093-1,038,753 forward strand.
R64-1-1:BK006945.2
This gene has 1 transcript (splice variant), 321 orthologues, 1 paralogue and is a member of 1 Ensembl protein family.