Zinc-knuckle transcription factor, repressor and activator; regulates genes involved in branched chain amino acid biosynthesis and ammonia assimilation; acts as a repressor in leucine-replete conditions and as an activator in the presence of alpha-isopropylmalate, an intermediate in leucine biosynthesis that accumulates during leucine starvation [Source:SGD;Acc:S000004443]
Chromosome XII: 1,036,093-1,038,753 forward strand.
R64-1-1:BK006945.2
This gene has 1 transcript (splice variant), 321 orthologues and 1 paralogue.
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
LEU3 | YLR451W_mRNA | 2661 | 886aa | YLR451W | Protein coding | P08638 | - | Ensembl Canonical, |