Saccharomyces cerevisiae (R64-1-1)
Description

ATP-dependent 5' to 3' RNA/DNA and DNA helicase; subunit of the exosome-associated Nrd1p complex that mediates 3' end formation of snRNAs, snoRNAs, CUTs and some mRNAs; helicase-independent role in transcription-coupled repair; coordinates replication with transcription, associating with moving forks and preventing errors that occur when forks encounter transcribed regions; homolog of Senataxin, implicated in Ataxia-Oculomotor Apraxia 2 and a dominant form of juvenile ALS [Source:SGD;Acc:S000004422]

Synonyms

CIK3, NRD2

Location

Chromosome XII: 993,434-1,000,129 forward strand.

R64-1-1:BK006945.2

About this gene

This gene has 1 transcript (splice variant), 237 orthologues, 2 paralogues and is a member of 2 Ensembl protein families.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
SEN1YLR430W_mRNA66962231aaYLR430W
 
Protein coding
Q00416 NM_001182318.3
NP_013534.3

Gene-based displays