Saccharomyces cerevisiae (R64-1-1)

Regulates transcription of ribosomal protein and biogenesis genes; regulates response to nutrients and stress, G2/M transitions during mitotic cell cycle and DNA-damage response, and modulates cell size; regulated by TORC1 and Mrs6p; sequence of zinc finger, ChIP localization data, and protein-binding microarray (PBM) data, and computational analyses suggest it binds DNA directly at highly active RP genes and indirectly through Rap1p at others; can form the [ISP+] prion [Source:SGD;Acc:S000004395]

Gene Synonyms

[ISP(+)], [ISP+]


Chromosome XII: 925,568-927,619 forward strand.


About this gene

This gene has 1 transcript (splice variant) and 302 orthologues.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
Protein coding
P32432 -Ensembl Canonical