ATPase of the CDC48/PAS1/SEC18 (AAA) family, forms a hexameric complex; is essential for pre-60S maturation and release of several preribosome maturation factors; releases Rlp24p from purified pre-60S particles in vitro; target of the ribosomal biosynthesis inhibitor diazaborine; may be involved in degradation of aberrant mRNAs [Source:SGD;Acc:S000004389]
DRG1
Chromosome XII: 912,550-914,892 reverse strand.
R64-1-1:BK006945.2
This gene has 1 transcript (splice variant), 369 orthologues and 4 paralogues.