Enzyme regulator; involved in synthesis of phosphatidylinositol 3,5-bisphosphate, in control of trafficking of some proteins to the vacuole lumen via the MVB, and in maintenance of vacuole size and acidity; binds negative (Fig4p) and positive (Fab1p) regulators of PtdIns(3,5)P(2) to control endolysosome function; similar to mammalian Vac14p [Source:SGD;Acc:S000004378]
Chromosome XII: 893,628-896,270 forward strand.
R64-1-1:BK006945.2
This gene has 1 transcript (splice variant), 228 orthologues and is a member of 2 Ensembl protein families.
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
VAC14 | YLR386W_mRNA | 2643 | 880aa | YLR386W | Protein coding | Q06708 | NM_001182275.3 NP_013490.3 |