Conserved ER protein translocation channel; essential subunit of Sec61 complex (Sec61p, Sbh1p, and Sss1p); forms channel for SRP-dependent protein import; with Sec63 complex allows SRP-independent protein import into ER; involved in posttranslational soluble protein import into the ER, ERAD of soluble substrates, and misfolded soluble protein export from the ER [Source:SGD;Acc:S000004370]

Chromosome XII: 875,736-877,178 reverse strand.

R64-1-1:BK006945.2

This gene has 1 transcript (splice variant), 305 orthologues, 1 paralogue and is a member of 2 Ensembl protein families.

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