Conserved ER protein translocation channel; essential subunit of Sec61 complex (Sec61p, Sbh1p, and Sss1p); forms channel for SRP-dependent protein import; with Sec63 complex allows SRP-independent protein import into ER; involved in posttranslational soluble protein import into the ER, ERAD of soluble substrates, and misfolded soluble protein export from the ER [Source:SGD;Acc:S000004370]
Chromosome XII: 875,736-877,178 reverse strand.
R64-1-1:BK006945.2
This gene has 1 transcript (splice variant), 385 orthologues and 1 paralogue.
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
SEC61 | YLR378C_mRNA | 1443 | 480aa | YLR378C | Protein coding | P32915 | - | Ensembl Canonical, |